Muddy River Marathon
Race Day Weather
Cool start, steady conditions
Runners will face a cool start at 43°F, rising to 64°F by the finish. Wind will be from the SSW at 17 mph, creating a consistent headwind throughout. With humidity at 65%, runners should maintain a steady pace and stay hydrated, particularly as temperatures rise later in the race.
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Race Info
The course passes several Cape Girardeau landmarks, including the Bill Emerson Memorial Bridge, the Common Pleas Courthouse, Dalhousie Golf Course and Old St. Vincent's Church, finishing along the Mississippi riverfront downtown near the Missouri Wall of Fame mural. The course is mostly flat, on city streets and paved trails. Proceeds benefit local nonprofits, including the Green Bear Project, Southeast Kids in Action, Graceful Opportunities and the Howard Aslinger Foundation; organizers have donated more than $100,000 to regional charities since the race began in 2021. The 2026 edition was cancelled due to street construction along the course route, with the race planning to return in 2027.